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Cover of The Gene: An Intimate History by Siddhartha MukherjeeThe Gene: An Intimate History
Modern · Nonfiction, Science, History

The Gene: An Intimate History

by Siddhartha Mukherjee
2016 · 560 pages · Nonfiction
Lifetime bestseller
≈ 14 hours to read · about 4 weeks at 30 minutes a day

What it's about

Siddhartha Mukherjee tells the history of the gene, from Mendel's peas and Darwin through eugenics and the Nazis, to the discovery of DNA, the Human Genome Project and gene editing. Running through it is his own family's history of mental illness, as he wonders what he and his children might have inherited.

Why it's worth reading

It hit #1 on the New York Times list. Mukherjee, who won a Pulitzer for The Emperor of All Maladies, makes hard science into a gripping story, and the personal thread makes it moving.

You'll love it if you liked

Good to know

It's long and the later chapters get technical. The history of eugenics is disturbing.

By the numbers

80.8Must-Read Score
  • Readers93 out of 100 · counts 42%
  • Critics0 out of 100 · counts 14%
  • Bestseller62 out of 100 · counts 34% (its stronger lane)
  • Buzz0 out of 100 · counts 10%

Critics and Bestseller are two ways to earn a place: a book's stronger one counts more. Buzz rewards recent bestseller weeks and prizes, so older books start at zero. The parts combine into the Must-Read Score, shown on a scale where the best book we found scores 99 and the last book to make the ranking scores 50.

Where it ranks

Why it made the list

Bestseller
#1 New York Times bestseller (1 week at #1)

Reads as

Thought-provoking, True story, Moving

How we rank

Already read it? Upload your Goodreads or StoryGraph history and get the 50 best books you haven't read, tuned to your taste.Get my 50

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Explore the best-of lists

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Quick answers

Is The Gene: An Intimate History worth reading?

Yes. It hit #1 on the New York Times list. It ranks #344 of the 2,816 books in our ranking, with a Must-Read Score of 80.8 (the best book we found scores 99).

What is The Gene: An Intimate History about?

Siddhartha Mukherjee tells the history of the gene, from Mendel's peas and Darwin through eugenics and the Nazis, to the discovery of DNA, the Human Genome Project and gene editing. Running through it is his own family's history of mental illness, as he wonders what he and his children might have inherited.

How long does it take to read The Gene: An Intimate History?

About 14 hours (560 pages), or about 4 weeks at 30 minutes a day.

What should I read after The Gene: An Intimate History?

If you liked it, try The Emperor of All Maladies: A Biography of Cancer by Siddhartha Mukherjee, The Code Breaker by Walter Isaacson or The Immortal Life of Henrietta Lacks by Rebecca Skloot.